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GeoffPainPhD's avatar

Congratulations on 1,825 reads so far on your Researchgate article.

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https://www.researchgate.net/post/AstraZeneca_Endotoxin_Contamination-Does_Adenovirus_or_other_ingredients_interfere_with_measurement

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Darrell O. Ricke, M.S., Ph.D.'s avatar

The initial COVID-19 mRNA and adenoviral vaccines raised antibody levels to SARS-COV-2 to very high levels. If the individual were to be exposed to a closely related strain of the virus, these antibodies have the potential to provide some protective benefits. Wang etc al showed with the SARS virus that it used Fc receptors on the surface of non-ACE2 phagocytic immune cells to infect some of them. Infected immune cells can disrupt the immune cells signals and enable the virus to spread quickly to other tissues prior to viral sepsis. So benefits from being vaccinated switch to negative risks - e.g., higher risk of infections (labeled breakthrough infections) and increased severity of disease for some vaccinated individuals as antibody levels naturally decrease with time (3 to 5 months). These patterns occur in parallel to adverse events and serious adverse events from the vaccines, including death (myocarditis/pericarditis if they survive, etc.).

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